Patients can present with the following signs & symptoms: CNS (areflexia, asthenia, ataxia, blurred vision, disorientation, dizziness, drowsiness, hyporeflexia, slurred speedh, somnolence, staggering, tiredness, coma) Cardiovascular (initial hypertension, followed by long-lasting hypotension , bradycardia , premature ventricular beats) the peripheral actions of xylazine cause an initial increase in blood pressure, followed by central effects that result in a long-lasting hypotensive effect, accompanied by bradycardia and reduced cardiac output (Hoffman et al, 2001)
Efficacy and safety of escalating the dose of oral semaglutide from 7 to 14 mg: a single-center, retrospective observational study
For further discussion of these and other risks and uncertainties, see Lilly's most recent Form 10-K and Form 10-Q filings with the United States Securities and Exchange Commission
What seems to matter most: What your appetite was like before you started How long you were on treatment Your dose Whether you built healthy habits you can maintain without the medication Should you taper off a GLP-1 or stop cold turkey