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Expert Commentary The rise of GLP-1 receptor agonists like semaglutide and tirzepatide reflects a major shift in how we approach both type 2 diabetes and obesity
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Nonneuropathic symptoms may include tightness, a vise-like squeezing of the feet, and the sensation of a sock rolled up at the end of the shoe
The conversion guidance that exists for transitioning between other GLP-1 agonists can provide some framework for thinking about dosing during transitions, though no specific tirzepatide-to-retatrutide conversion protocol has been established in clinical literature
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