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Sorafenib, a multiple kinase inhibitor and FDA approved drug, was revealed to induce ferroptosis and exhibit anti-tumor effects in various cancer cell lines such as hepatocellular carcinoma cells, human kidney cancer cells and nonsmall cell lung cancer [131, 132]

The takeaway is straightforward: researchers are paying close attention to whether tirzepatides metabolic effects translate into measurable heart outcomes, not just better A1C numbers or weight loss

doi: 10.3389/fphar.2024.1384834 Received 10 February 2024 Accepted 04 April 2024 Published 01 May 2024 Volume 15 - 2024 Edited by Norsham Juliana, Universiti Sains Islam Malaysia, Malaysia Reviewed by Marjanu Hikmah Elias, Universiti Sains Islam Malaysia, Malaysia Khairun Nain Bin Nor Aripin, Islamic Science University of Malaysia, Malaysia Updates Copyright 2024 Hassan, Abdel-Halim, El-Shenbaby, Helmy, Hammad, Habotta, El Nashar, Alghamdi, Aldahhan, Al-Khater, Almohaywi and Farrag

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