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Abbreviations AAV: Adeno-associated viruses AuNPs: Gold nanoparticles BMPO: 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide CAT: Catalase CDFI: Color doppler flow imaging CH: Congenital hydronephrosis CTPO: 5-Carboxy-2,2,5,5-tetramethyl-1-pyrrolidinyloxy DEGs: Differentially expressed genes DEPs: Differentially expressed proteins DLS: Dynamic light scattering DMEM: Dulbeccos modified eagle medium DMPO: 5,5-Dimethyl-1-pyrroline N-oxide DTT: Dithiothreitol ESR: Electron spin resonance FBS: Fetal bovine serum FDR: False discovery rate GAPDH: Glyceraldehyde 3-phosphate dehydrogenase GEO: Gene expression omnibus GSH-Px: Glutathione peroxidase H&E: Hematoxylin and eosin HD: Hydrodynamic diameter HK-2: Human kidney-2 HRP: Horseradish peroxidase IACUC: Institutional animal care and use committee ICP-MS: Inductively coupled plasma mass spectrometry IHC: Immunohistochemistry KEGG: Kyoto encyclopedia of genes and genomes LASSO: Least absolute shrinkage and selection operator LC-MS/MS: Liquid chromatography-tandem mass spectrometry MDA: Malondialdehyde MF-NZ: Multifunctional nanozyme OS: Oxidative stress PBS: Phosphate-buffered saline PFA: Paraformaldehyde PMIZ-AuNPs: pH-responsive PEG-SH and imidazole-modified gold nanoparticles POBN: -(4-Pyridyl 1-oxide)-N-tert-butylnitrone PPI: Protein-protein interaction RCT: Renal cortical thickness RF: Renal fibrosis RIF: Renal interstitial fibrosis RI: Resistance index ROS: Reactive oxygen species RT-qPCR: Reverse transcription quantitative polymerase chain reaction SOD: Superoxide dismutase TEM: Transmission electron microscopy TGF-: Transforming growth factor beta TKPTS: Mouse and human proximal kidney tubular cells UCA: Ultrasound contrast agent UUO: Unilateral ureteral obstruction WB: Western blot -SMA: Alpha-smooth muscle actin OH: Hydroxyl radicals References Rai A, Hsieh A, Smith A
Cardio heart
Sometimes frozen HGH looks normal but has lost 50 to 100 percent of its potency (invisible damage), which is why the "never freeze" rule is absolute regardless of what the vial looks like afterward
Chinese and Peruvian ginger root is the primary ingredient in our botanically brewed ginger base
