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Although not all microbial challenges trigger this primed response, the naturally existing fly pathogen Beauveria bassiana may also confer a distinct protection against the fungus upon a second encounter ( Drosophila research has contributed the majority of our understanding of insect innate immunity through genetic studies of the antimicrobial peptide response, paving way for the study of Toll-like receptors, which play an important role in the innate immune response of mammals