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The Bottom Line Heartburn on a GLP-1 isn't inevitable, but it is common and manageable

Bottom Line None of the ingredients commonly found in GLP-1 patches such as green tea extract, garcinia cambogia, guarana, bitter orange, berberine, and others have been proven to affect GLP-1 activity

Eating Smaller Meals To avoid feeling nauseated, you might need to make some changes to your routine

Statins (cholesterol drugs): examples include lovastatin (Mevacor), atorvastatin (Lipitor), simvastatin (Zocor), simvastatin/ezetimibe combination Interaction: Grapefruit can increase blood levels of these statins, raising the risk of muscle toxicity, known as rhabdomyolysis Safer alternatives include: rosuvastatin (Crestor), fluvastatin (Lescol), pravastatin (Pravachol), Calcium channel blockers (blood pressure drugs): examples include amlodipine (Norvasc), diltiazem (Cardiazem, Tiazac), felodipine (Plendil), nifedipine XL (Adalat XL), verapamil (Isoptin SR, Verelan) Interaction: Increased drug levels may cause hypotension, dizziness or edema Antiarrhythmics (atrial fibrillation drugs): examples include amiodarone (Cordarone), disopyramide (Norpace) Interaction: Increased risk of QT prolongation, arrhythmia and other side effects