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The National Institute for Health and Care Excellence guidelines for pernicious anaemia are due to be published in 2023

And what I found in [00:38:00] my research that up until about the age of 30, there is no need for any supplementation

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The mechanisms for these include: decreased fibrinolytic activity in vessel walls, increased oxidative stress in endothelial cells, and possibly increased intracellular calcium in vascular smooth muscle cells (161, 162, 192)