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Indirect effects An indirect pathway for GLP-1RAs to mediate risk for PDAC is via acute or chronic pancreatitis, which are risk factors for PDAC 24,25
GLP-1 receptor agonists (GLP-1RAs or GLP1s) like semaglutide have been proven to reduce body weight and lessen cardiovascular (CV) risk in patients with type 2 diabetes, butuntil SELECT was publishedthey had not been shown to improve cardiovascular outcomes in patients with a high BMI (aka the obese and overweight**) without diabetes
This is thought to explain its greater efficacy compared to semaglutide alone
Diet soda may seem like a harmless swap, but for some people, it can increase cravings for sweet foods or alter gut bacteria in ways that dont support digestive or metabolic health
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