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In a phase 3 clinical trial, tirzepatide reduced 14.9% of body weight with a 5 mg dose, 19.5% with a 10 mg dose, and 20.9% with a 15 mg dose of tirzepatide

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A principal component analysis (PCA) was then conducted to capture the main variation axes, resulting in a 50-component matrix generated by the RunPCA function

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