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306 Intrinsic nuclear PD-L1 can also cooperate with p-STAT3 to upregulate IL-6, activating MDSCs through the IL-6/JAK/STAT3 axis in a PD-1independent manner

They found that glutathione protects skin cells from oxidative damage and premature ageing caused by UV and pollution

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In about 17,600 adults with obesity and established cardiovascular disease but no diabetes, semaglutide cut major cardiovascular events by 20% over roughly 40 months. This is a secondary-prevention result in people who already had heart disease