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Most adverse effects are dose-dependent and tend to improve over time as the body adjusts to the medication
A Cochrane systematic review of NAC for COPD exacerbations (39 RCTs, n=7,436) found that NAC and other mucolytics significantly reduced the frequency of acute exacerbations (OR 0.75, 95% CI 0.62-0.92) (Poole et al., Cochrane Database Syst Rev, 2019) [43]
More important than my observation is the following: In comments by Thompson and Sturmer published in the journal Diabetes Care in 2023, about a study of GLP-1s and the risk of thyroid cancer conducted by Bezin et al which was published in the same journal issue, Thompson and Sturmer conclude that Thyroid cancer is a rare outcome, however, and the potential increase in absolute risk is very small
(2023, July 14)
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