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In this study, as amino acid precursors could be fed to improve concentrations of intracellular free l-cysteine, we resorted to overexpression of GK instead of loss-of-function mutations in GPR for accumulation of -glutamyl phosphate to strengthen the redirection of -glutamyl phosphate to GSH synthesis

10.1111/j.1365-2125.2012.04172.x 3 DrmicD.KolencD.IlicS.BaukL.SeverM.Zenko SeverA.et al (2017)