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The reduction in brain volume with RT has been observed in pharmaceutical trials for AD, and is hypothesized to be related to reduction in A load (Fox et al., 2005)
While researchers have questioned whether GLP-1s could help with Parkinsons, a recent clinical trial did not show any overall impact
Tirzepatide may show faster appetite suppression than semaglutide due to its dual mechanism (GLP-1 + GIP agonist)
Failure to report adverse events: A November 2025 California Board of Pharmacy petition to revoke Empower Pharma's license cited numerous adverse effects, including three urgent care visits following semaglutide and B12 injections
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