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However, it often is challenging, expensive and time-consuming to develop and test the effectiveness of such interventions and translational animal models that are adequately mimicking the underlying physiological pathways are scarce

Aim for adequate protein intake (1.2-1.6 g/kg/day) to preserve lean muscle mass during weight loss, with guidance from a registered dietitian, especially if you have kidney disease

Nuclear staining was performed with Hoechst staining (Becton-Dickinson Biosciences, San Jose, CA)

It is important to know the degree of symptoms to know when to contact emergency services or seek medical guidance