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Metformin is available as a brand-name drug (Fortamet, Riomet) and in a generic form

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It is designed to bind GHRH receptors on pituitary somatotroph cells, prompting the body's own pituitary gland to release growth hormone (GH), which in turn raises downstream IGF-1 levels

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This data suggests that more healthcare providers are seeing the benefits of these medications for treating obesity, which is a significant public health shift, said Yee Hui Yeo, MD, co-first author of the study and a clinical fellow in the Karsh Division of Gastroenterology and Hepatology at Cedars-Sinai

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