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GLP-1 receptor agonists (RAs) were originally developed to treat type 2 diabetes mellitus (T2DM) and have been FDA-approved for this indication since 2005
The lawsuit also argues that Zepbound has been proven to be more effective for weight loss, and, on its formulary page for the switch, CVS acknowledges that studies with that implication exist while saying "real-world evidence suggests the two are comparable." "Because of their different methods of action, different clinical outcomes, and different side effects for individual patients, Zepbound and Wegovy are not clinically interchangeable," the plaintiffs said in their complaint
Naloxone administration is reasonable in patients with mild-moderate intoxication
Psychiatry 21 , 823830 (2016)
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