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Because thyroid hormone synthesis by thyroid peroxidase (TPO) requires hydrogen peroxide (H2O2), adequate glutathione is needed to neutralise excess reactive oxygen species and protect thyroid follicular cells from oxidative damage and immune-mediated inflammation

Specifically, the activated receptor possibly engages a class of G proteins referred to as Gq/11, which in turn may stimulate an enzyme called phospholipase C (PLC)

This modifier indicates that the evaluation and management service is separate from the vaccine administration