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The cells in these hypoxic regions are resistant to both radiotherapy and chemotherapy

Abnormalities in the expression or function of FOXO6 have been identified as a pathophysiological basis for the development of fasting hyperglycemia and hyperlipidemia, which are serious metabolic complications in diabetic patients

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From there, the trial product estimand and the treatment policy estimand were used to assess the efficacy of the treatment in all randomly assigned participants