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Laboratory studies examine receptor activation, cyclic adenosine monophosphate (cAMP) signaling, kinase activation, intracellular trafficking, second messenger communication, transcriptional regulation, peptide metabolism, and molecular adaptation following peptide-receptor interaction
PKA phosphorylates aralkylamine N -acetyltransferase activating this enzyme required for melatonin synthesis
190 TLSs allow replicative bypass of alkylated or crosslinked lesions and prevent replication fork collapse
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