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While the detailed regulatory mechanisms remain largely unexplored, we utilized the well-established developmental cell fate transition model PNT to reveal that inhibition of METTL3, either through pharmacological intervention or genetic manipulation, significantly promotes PNT efficiency

And another question that you had sort of already alluded to is where in your progression of treatments you tend to use [00:17:00] GLP-1s, like we got a lot of questions that were basically, what would you try first

Cardiovascular Protection: GLP-1s are proven to lower blood pressure and improve cholesterol levels

The interval time was 10 min between each dose [36,37,38]