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-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/mTOR signalling pathways
Malhotra et al
It carries fatty acids into the mitochondria of each cell, where they are oxidized and stored as ATP, a prime energy fuel.*
Taken together, these elaborate mechanisms highlight the UPR not as a uniform survival pathway but as a dynamic, branch-specific signaling network whose outputs depend on tumor type, microenvironment, and stress duration
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