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doi:10.1016/S0140-6736(23)01053-X 3
At 14 weeks of age, mice were randomized into treatment groups ( n = 8 per group) receiving subcutaneous injections of PG-102 (15, 30, 60, or 120 nmol/kg), semaglutide (30 nmol/kg), tirzepatide (15 nmol/kg), or vehicle every 3 days for 12 weeks
A 56 percentage point difference is real and clinically meaningful at scale especially for patients with severe obesity who need maximum weight loss
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