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However, it's important to note that such reports cannot establish causality or frequency of these symptoms

Also, both mutant and WT SOD1 produce cytotoxic levels of H 2 O 2 via a cysteine redox regulation system (Bakavayev et al., G93A mice show significantly increased protein carbonyl levels in the spinal cord, including elevated carbonylation of mutant SOD1, which has been linked to motor neuron degeneration (Poon et al., 2005)

Some people find that room-temperature water is easier to tolerate than cold water during periods of nausea