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Cancer progression due to hyperglycemia was reported in multiple cancers, including breast, colorectal, brain, and pancreatic cancer [22,23,24,25]

To achieve this, we blocked GLP-1R or GCGR with the antagonists exendin 9-39 (Ex9-39) and des-His1-[Glu9]-Glucagon (1-29) amide (GCGRant), respectively

Front Immunol 12:774013 Karhu ST, Ruskoaho H, Talman V (2021) Distinct regulation of cardiac fibroblast proliferation and transdifferentiation by classical and novel protein kinase C isoforms: possible implications for new antifibrotic therapies