Here's what physicians typically weigh when comparing them: Effectiveness: In the SURMOUNT and SURPASS trials, tirzepatide showed average weight loss of 15-22% of body weight at higher doses
Since then, several GLP-1s for obesity have been approved for new indications, such as secondary cardiovascular risk reduction (Wegovy), sleep apnea (Zepbound) and metabolic dysfunction-associated steatohepatitis, or MASH (Wegovy)
D., & Schaff, H
Yilmaz M, Muftuoglu M, Short NJ, Loghavi S, Kadia TM, DiNardo CD, Borthakur G, Pemmaraju N, Valero YA, Maiti A, Konopleva M, Masarova L, Montalban-Bravo G, Jurisprudencia C, Pike A, Patel KP, Tang G, Matthews J, Kornblau SM, Jabbour E, MD, Garcia-Manero G, Takahashi K, Andreeff M , Ravandi F, Kantarjian HM, Daver N