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Several rodent studies link BPC-157 to the VEGF-receptor-2 / Akt / endothelial nitric oxide synthase (eNOS) signaling axis, which would connect its reported angiogenic and vasodilatory effects to a single upstream pathway
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Limitations & Considerations Much of the published literature on this copper-peptide complex comes from in-vitro and animal-model work rather than large randomized trials, so effect sizes reported in one system do not automatically transfer to another
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