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Subjective markers also provide valuable efficacy signals

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doi: 10.1172/jci.insight.140532 46 VilsbollTKnopFKKrarupTJohansenAMadsbadSLarsenSet al

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But in reality, while theres some potential in increasing GLP-1 in animals, human evidence is mixed

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In some contexts, FPR2 deficiency reduces macrophage infiltration and attenuates lesion development, whereas in others, it lowers collagen content and increases plaque instability [130]

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