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INTRODUCTION Cell culture The rat aortic A-10 VSMC line was purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA) and was cultured in Dulbeccos modified Eagles medium (DMEM) high glucose (25 mmol/L, Gibco, Grand Island, NY, USA) supplemented with 10% fetal bovine serum (FBS, Hyclone, Logan, UT, USA) and 1% penicillin/streptomycin (Gibco) in an incubator at 37C with a humidified atmosphere of 5% CO 2 in the air
Bacteroides acidifaciens and Blautia coccoides , which may contribute to the production of acetate ( Furthermore, Kato et al
(ii) increasing cell autophagy and inhibiting the mitogenic mitogen activated protein kinases (MAPKs) (JNK/ SAPK) pathway [226]
