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It is quickly degraded into its inactive form (9-36) after selective cleavage by dipeptidyl peptidase-4 (DPP-4)
Tu, Ho-Schleyer, Travers, & Weissman, 2000
Gradual titration Always start the new GLP-1 medication at a low dose and titrate it up slowly and gradually to minimize the risk of gastrointestinal adverse effects, even if you were previously on a high dose of a GLP-1 medication
Presented for research literature review only Kuo CC et al
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