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In previous studies, FOXO4 and p53 have been shown to interact, a process that inhibits the pro-apoptotic role of p53 by restraining its nuclear exclusion, thereby promoting cell survival

Treatment protocols are typically individualized based on health goals and clinical guidance

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Furthermore, the associations between gut solute paracellular permeability and circulating endotoxin concentrations should not be regarded as cause and effect, but rather increased gut paracellular permeability should be regarded as a useful biomarker for systemic inflammation