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Conceptual confluence: the kynurenine pathway as a common target for ketamine and the convergence of the inflammation and glutamate hypotheses of depression

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Similarly, other studies indicate that enhanced PS exposure may result in a pathological erythrocyte procoagulant phenotype, which may contribute to the development of a hypercoagulable state

Model Selection: Choose appropriate experimental systems: In vitro: Pituitary cell cultures, somatotroph cell lines Ex vivo: Pituitary tissue explants, hypothalamic-pituitary preparations In vivo: Age-matched animal models with appropriate controls 6