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HSS Journal: The Musculoskeletal Journal of Hospital for Special Surgery , 21(3), 115

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In one study, participants received weekly doses of Cagrilintide and experienced significant body weight reductions ranging from 6% to 11% in just six weeks

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Then, the researchers administered exendin-4 via intrathecal injection to the experimental rats and observed a reduction in pain sensitivity, alleviation of neural inflammation, and suppression of inflammatory factors such as IL-1, TNF-, and iNOS

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