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In the CNS, GLP-1 also exert neuroprotective and neurotropic effects by binding to GLP-1R (20, 22, 116)
Even in these cases, semaglutide would not typically be part of a standard drug test unless there was a specific reason to check for it
Two authors (DM and SS) independently reviewed and selected studies for inclusion and subsequently resolved discrepancies by discussion
This roughly mirrors the trial schedule used in the Phase 2 and Phase 3 studies
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