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Clear titration protocol matching trial schedules (semaglutide ramping from 0.25 mg over months
The interactions between GLP-1RAs and other drugs may affect drug efficacy or increase the risk of adverse reactions, as well as the dose adjustment of the combination of hypoglycemic drugs, which put forward higher requirements for clinicians
This is crucial for preventing atherosclerotic plaque formation and maintaining vascular elasticity (Liu et al., 2018)
But their health outcomes are dramatically different
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