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Chronic Inflammation Linked to Metabolic and Heart Disease Chronic inflammation creates a domino effect: It stiffens arteries, triggering high blood pressure and a greater risk of heart attacks and strokes. Cells become more resistant to insulin, making diabetes more likely and harder to control
From the Australian public healthcare perspective, this came at an incremental cost of AU$4.2 billion for SGLT2is and AU$20.2 billion for GLP-1 RAs, with corresponding ICERs of AU$23,717 and AU$100,705 per QALY gained, respectively
But, even if it is the case that the risk of thyroid cancer turns out to be complete noise, it still wouldnt change the fact that most people would be better off avoiding GLP-1 agonists for the reasons listed here
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