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The REWIND trial, targeting cardiovascular events in T2DM participants without previous cardiovascular history, found that dulaglutide reduced cardiovascular outcomes, and was well tolerated [61]
Ozdemir Kutbay et al., 2020) in several TC models ( These in vitro studies make metformin desirable for potential repositioning as anti-cancer compounds in the treatment of TC, thus several studies are still ongoing to deeply characterize its effect
The Wegovy medication lists depression as a potential side effect and the FDA has Tirzepatide demonstrated the most significant decrease in developing depression among diabetic patients
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