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Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide
Goldstein J, Kirwin J, Seymour N, Trachtenberg J, Rademaker E, Andersen D
There is a bidirectional link between the two phenomena: an increase in permeability promotes dysbacteriosis (29), and the changes in the microbiota can also modify intestinal permeability (30, 31)
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