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The peptide stimulates production of VEGF (vascular endothelial growth factor) and HGF (hepatocyte growth factor), both critical for building new capillary networks
Rosmond et al., 1998
However, the minor allele at rs12720356 was found to have no effect on STAT phosphorylation or cytokine production, while the protective allele at rs3456443 did reduce phosphorylation and cytokine stimulation in peripheral blood immune cells (121)
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