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Yes, high-dose B12 therapy can ease symptoms like paresthesia and burning sensations
Neurological symptoms such as tingling or numbness are more commonly associated with B12 deficiency rather than excess and warrant medical assessment
doi:10.1073/pnas.62.2.461
If you find the 45 unit mark uncomfortably small to read, the honest options are (a) use a finer-gradation syringe, or (b) follow a protocol built around the 50 mg vial, whose larger draw is more forgiving not to freehand a bigger volume from the 10 mg vial, which would silently overdose relative to the documented figure
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