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Description

The safety profile is generally favorable, with most side effects being GI-related (nausea, constipation, diarrhea) that improve with time and gradual dose escalation

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Hostnek JJ, Dreher F, Maibach HI

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In many cases, copper deficiency may be the missing piece

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Whilst injections bypass gut absorption, conditions like active Crohn's disease or coeliac disease may cause increased metabolic demands that could influence how quickly B12 is utilised

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