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NFS1 degrades cysteine and releases sulphide, which can be used to generate ironsulphur (FeS) clusters, 138 versatile co-factors that carry out electron transfer, catalysis and afford structural stability

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Notably, tumor cells do not operate in isolation

[11C]-Labeled metformin distribution in the liver and small intestine using dynamic positron emission tomography in mice demonstrates tissue-specific transporter dependency