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Gameiro S, Finnigan A
Recently, three new axes have been identified, emphasizing the role of the kidney in this picture (22): The ACE2/ANG(1-7)/Mas receptor pathway (23, 24): Ang-(1-7) binds to the G protein-coupled receptor Mas, which is expressed in renal proximal tubular cells, afferent arterioles, cardiac myocytes, and neuronal cells
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A significant number of those with Type 1 can also then develop insulin resistance as well from the high carbohydrate intake, necessitating the use of large amounts of insulin
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