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Adverse drug interactions may occur with some antifungals, antibiotics, medications for abnormal heartbeat and anti-seizure medications

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In human vitiligo melanocytes (PIG3V) induced by hydrogen peroxide, baicalein increased the expression of Nrf2 and its downstream gene HO-1 in PIG3V cells, promoted the translocation of Nrf2 from cytoplasm to nucleus, indicating that the protective effect of baicalein on melanocytes depends on Nrf2 signaling pathway (Ma et al., 2018)