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NICE Symptoms to watch for (because numbers arent everything) Contact your clinician if you notice new symptoms that persist for a couple of weeks, such as: Possible under-replacement (hypothyroid): fatigue, low mood, feeling cold, constipation, dry skin, slower heart rate Possible over-replacement (hyperthyroid): palpitations, tremor, anxiety, sweating, heat intolerance, diarrhoea, trouble sleeping These symptoms can overlap with diet changes and early Mounjaro side effects, so blood tests help clarify whats going on
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