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C9orf72 also forms a complex with SMCR8 and WDR41 in the regulation of autophagy, and it is also implicated in autoimmunity, immune dysregulation, endocytosis, and lysosome homeostasis (Atanasio et al., 2016
For use within a few days or weeks, refrigeration at approximately 4C (39F) is generally sufficient
This biased signaling profile may reduce receptor internalization and desensitization, theoretically maintaining receptor responsiveness with chronic treatment
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