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Compulsive use, marked by an inability to abstain or limit intake in spite of awareness of harmful outcomes, is a defining characteristic of substance use disorders (SUDs) (Health et al., 1988
The microbiome, the entire gut immune system, the nervous system, immune response
Over the previous 18 months, hed lost 91 pounds, coming down from a high of 285 after a COVID-era leg injury left him sidelined from physical activity
Discontinuation reverses outcomes: participants who stopped semaglutide at week 20 in the STEP-1 withdrawal design regained two-thirds of their lost weight by week 68 [11]
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