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It contains a trace amount of calories (less than 5 per serving), which can be displayed as zero calories on the label under the Food and Drug Administration (FDA) Code of Federal Regulations
If you do drink, do so with food, slowly, and in moderation and never on an empty stomach
Impact of Semaglutide on fat mass, lean mass and muscle function in patients with obesity: The SEMALEAN study
It's worth noting that other GLP-1 receptor agonists such as liraglutide and semaglutide are based on human GLP-1 analogues rather than exendin-4
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