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Many studies show that berberine can significantly reduce blood sugar levels in individuals with type 2 diabetes In fact, its effectiveness is comparable to the popular diabetes drug metformin (Glucophage) It seems to work via multiple different mechanisms Decreases insulin resistance, making the blood sugar lowering hormone insulin more effective

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The subcutaneous fat in the abdominal area also tends to be more vascularized, meaning it has a denser network of small blood vessels running through it

Liraglutide and semaglutide: pooled post hoc analysis to evaluate risk of dementia in patients with type 2 diabetes