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If your BMI is below 27, it might be better to focus on losing weight without medication and on developing healthier, sustainable habits

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In summary, our approach demonstrates the feasibility of using peptide-mediated targeting to achieve cell-specific ionotropic receptor modulation and highlights the therapeutic potential of unimolecular mixed GLP-1 receptor agonism and NMDA receptor antagonism for safe and effective obesity treatment

Psoas volume and fat content were assessed from liver MRIs and physical function was measured by chair-rise and gait speed tests at baseline and six months