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L-Phenylalanine also promotes the release of cholecystokinin (CCK), a hormone known for producing feelings of food satisfaction and fullness, which can help reduce the desire for food and decrease overall food intake
The GHK motif itself occurs within the alpha-2(I) chain of type I collagen, so it is commonly classified as a matrikine, a fragment liberated during matrix degradation that signals back to the cells that deposited it
Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R
10.1126/science.aaw5473 77 FaubertB.VincentE
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